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KMID : 0361020020450121162
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Korean Journal of Otolaryngology - Head and Neck Surgery
2002 Volume.45 No. 12 p.1162 ~ p.1166
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Eosinophilic Nonallergic Rhinitis : Clinical Characteristics and Efficacy of Nasal Steroids
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이봉재/Bong Jae Lee
이시형/김재호/김용재/박효진/Si Hyung Lee/Jae Ho Kim/Yong Jae Kim/Hyo Jin Park
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Abstract
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Background and Objectives: Although eosinophilic nonallergic rhinitis (ENR) is a well recognized entity, its clinical features and the response to the treatment have not been definitively elucidated. Authors aimed to investigate the
clinical
characteristics of ENR and the response to the nasal steroids. Materials and Method: A prospectively study was conducted for 59 patients diagnosed as ENR at the department of Center between 1994 and 2001. Diagnostic criteria include
rhinitis
symptoms lasting more than 3 months, nasal eosinophilia, and negative results for allergic skin test or MAST. Patients were treated with nasal steroids for three weeks and compared the pre-treatment and post-treatment symptom scores.
Results: Of
59 patients, 25 were males and 34 females. Their age ranged from 6 to 67 years (average : 35 years). Nasal obstruction was most frequently complained by the patients, followed by rhinorrhea, and sneezing. The percentage of nasal secretion
eosinophils
ranged from 10 to 100% with a mean of 71%. Treatment with topical steroids was effective in 53 patients (90%) to relieve symptoms. Conclusion: Unlike allergic rhinitis, ENR commonly develops in the adults with an average age of 31 years.
Topical
steroid is effective in 90% of patients to relieve rhinitic symptoms. Differential diagnosis of chronic rhinitis using allegic skin test and nasal secretion eosinophils is needed for the adequate treatment.
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KEYWORD
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